8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride CAS 2193067-92-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2193067-92-2
Molecular FormulaC8H9ClN2
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride CAS 2193067-92-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 205.08 g/mol gives 8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride (CAS 2193067-92-2) is a high-purity analytical reference standard with the molecular formula C8H9ClN2HCl and a molecular weight of 205.08 g/mol.

The molecular framework of 8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride (C8H9ClN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-Chloro-1,2,3,4-tetrahydro-2,7-naphthyridine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H9ClN2 2*HCl
Molecular Weight205.08 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentCl-containing
Nitrogen Atoms2

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