4-(Phenylethynyl)phthalic acid CAS 219537-88-9
| CAS No. | 219537-88-9 |
| Molecular Formula | C16H10O4 |
| Molecular Weight | 266.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Phenylethynyl)phthalic acid is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(Phenylethynyl)phthalic acid (CAS 219537-88-9), a certified reference material (molecular formula C16H10O4, MW 266.25 g/mol) for analytical method development and quality control.
Structurally, 4-(Phenylethynyl)phthalic acid (C16H10O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 266.25 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Phenylethynyl)phthalic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10O4 |
| Molecular Weight | 266.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
Related Phenylethynyl Standards
- 5-(Phenylethynyl)isophthalic acid (CAS 432025-99-5)
- N-[4-(2-Phenylethynyl)phenyl]butanamide (CAS 439097-37-7)
- N-(4-(phenylethynyl)phenyl)cyclopropanecarboxamide (CAS 439095-65-5)
- N-(4-(phenylethynyl)phenyl)methanesulfonamide (CAS 439095-76-8)
- 8-(Phenylethynyl)-1-naphthaldehyde (CAS 1850307-81-1)
- 2-(Phenylethynyl)-1,1'-biphenyl (CAS 10271-65-5)
- 1,3-Bis(phenylethynyl)benzene (CAS 13141-36-1)
- 1,4-Bis(phenylethynyl)benzene (CAS 1849-27-0)
Recommended Standards
- 4-(Difluoromethyl)-2-hydrazinyl-6-(3-methoxyphenyl)pyrimidine (CAS 861226-63-3)
- 4,4'-(Ethyne-1,2-diyl)bis(2-hydroxybenzaldehyde) (CAS 791068-96-7)
- 4-(5-Phenyl-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 85292-45-1)
- 4,5-Phenanthrenedicarboxylic acid, 97% (CAS 5462-82-8)
- n-(4-Chlorobenzyl)-1-methoxypropan-2-amine (CAS 1019628-28-4)
- 2-(Thiophen-3-yl)benzoic acid (CAS 20608-87-1)
- 3-butyn-2-one (CAS 1423-60-5)
- 2-Nitro-1-propanol (CAS 2902-96-7)
- Hexane-1,6-diamine xadipate (CAS 15511-81-6)
- 1-Fluoro-2-prop-2-ynoxybenzene (CAS 113714-11-7)
- 1-Methoxy-9H-fluorene (CAS 26060-14-0)
- 3-Trifluoromethylphenylthioethanol (CAS 548739-94-2)
- 4,7-Dimethyl-2,3-dihydrobenzofuran-3-amine (CAS 1156986-73-0)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
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