4’-Methoxy-2-chloroacetophenone CAS 2196-99-8
| CAS No. | 2196-99-8 |
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4’-Methoxy-2-chloroacetophenone.
4’-Methoxy-2-chloroacetophenone (CAS 2196-99-8) is a high-purity analytical reference standard with the molecular formula C9H9ClO2 and a molecular weight of 184.62 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4’-Methoxy-2-chloroacetophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4’-Methoxy-2-chloroacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2 |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Methoxy Standards
- 2-Methoxy-2-phenylacetyl chloride (CAS 39098-93-6)
- 2-methoxy-3-methylbenzoyl chloride (CAS 22256-43-5)
- 2-Methoxy-5-methylbenzoyl chloride (CAS 25045-35-6)
- 2-Methoxy-6-methylbenzoyl chloride (CAS 50463-84-8)
- 3-Methoxy-5-methylbenzoyl chloride (CAS 96227-40-6)
- 4-Methoxy-3-methylbenzoyl chloride (CAS 59931-48-5)
- 3-Methoxy-4-methylbenzoyl chloride (CAS 87808-44-4)
- 4-Methoxy-1-(pyrrolidin-3-yl)piperidine (CAS 1249760-60-8)
Recommended Standards
- 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine-3-carbonyl chloride (CAS 307307-99-9)
- 4-Amino-2-chloro-n-methylbenzamide (CAS 926203-17-0)
- 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine-2-carbonyl chloride (CAS 307313-04-8)
- 4-Amino-3-chloro-n-methylbenzamide (CAS 408316-92-7)
- 5-(Sec-butyl)-3-methylisoxazole-4-carboxylic acid (CAS 1263378-15-9)
- 2-Chloro-N-(4-(methylthio)benzyl)acetamide (CAS 1353975-78-6)
- (3R,7aS)-3-(tert-Butyl)dihydropyrrolo[1,2-c]oxazole-1,5(3H,6H)-dione, 97% (CAS 171284-84-7)
- 2-((4,5-Diphenyl-1H-imidazol-2-yl)thio)acetic acid (CAS 20650-29-7)
- Dimethyl 2-(Phenylamino)-2-butenedioate (CAS 54494-74-5)
- 4-Tert-butyl-N-[4-(4-tert-butylbenzamido)phenyl]benzamide (CAS 57844-41-4)
- Pantoprazole Impurity 77 (CAS CATO-C4X-139977)
- cis-3-(methoxymethyl)cyclobutan-1-amine hydrochloride (CAS 1068160-25-7)
- 3-(Bromomethyl)-4-(difluoromethyl)-5-fluoropyridin-2-amine (CAS 1804726-45-1)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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