N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanylglycylglycine CAS 219677-70-0
| CAS No. | 219677-70-0 |
| Molecular Formula | C28H27N3O6 |
| Molecular Weight | 501.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanylglycylglycine.
CATO supplies N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanylglycylglycine (CAS 219677-70-0), a certified reference material (molecular formula C28H27N3O6, MW 501.53 g/mol) for analytical method development and quality control.
The molecular framework of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanylglycylglycine (C28H27N3O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H27N3O6 |
| Molecular Weight | 501.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Nitrogen Atoms | 3 |
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