1-Iodo-4-(4-nitrophenoxy)benzene CAS 21969-05-1
| CAS No. | 21969-05-1 |
| Molecular Formula | C12H8INO3 |
| Molecular Weight | 341.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Iodo-4-(4-nitrophenoxy)benzene (CAS 21969-05-1), a certified reference material (molecular formula C12H8INO3, MW 341.10 g/mol) for analytical method development and quality control.
1-Iodo-4-(4-nitrophenoxy)benzene (C12H8INO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-Iodo-4-(4-nitrophenoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8INO3 |
| Molecular Weight | 341.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- N-(5-iodo-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide (CAS 145913-85-5)
- 1-Iodo-2-(2-nitrophenoxy)benzene (CAS 860465-22-1)
- 4-Iodo-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxylic acid (CAS 913378-49-1)
- N-(5-Iodo-4-oxo-1,4-dihydropyrimidin-2-yl)benzamide (CAS 667411-75-8)
- Methyl 2-iodo-5-sulfamoylbenzoate (CAS 1342849-61-9)
- 3-Iodo-5-methoxy-6-(trifluoromethyl)-1H-indole (CAS 1171918-93-6)
- 5-Iodo-2-((4-methoxybenzyl)oxy)pyridine (CAS 1192064-49-5)
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Recommended Standards
- 4-bromo-2-formylphenyl 2,6-difluorobenzoate (CAS 646989-39-1)
- 1-Chloro-2-[(4-chlorophenyl)difluoromethyl]-4-(trifluoromethyl)benzene (CAS 95998-70-2)
- 1-(3-iodophenoxy)-2-nitrobenzene (CAS 332370-79-3)
- bis(4-Chloro-3-nitrophenyl)methanone (CAS 7498-65-9)
- 1-(1-Methyl-1H-benzo[d]imidazol-2-yl)piperidin-3-amine hydrochloride (CAS 1185311-18-5)
- 2-(3-Methylcyclohexyl)cyclohexan-1-ol (CAS 1342663-72-2)
- 1-Methyl-1H-pyrazolo[3,4-b]pyrazin-3(2H)-one (CAS 117883-61-1)
- Ethyl 2-((5-formylpyrimidin-2-yl)amino)acetate (CAS 915920-21-7)
- 1,2-dimethyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,3-benzodiazole (CAS 227306-27-6)
- (2,5-Diethylphenyl)methanamine (CAS 771469-84-2)
- Nicergoline (CAS 27848-84-6)
- 2-(N-(tert-butyldimethylsilyl)-S-(fluoromethyl)sulfinimidoyl)pyridin-3-olate (CAS 2050545-76-9)
- 3-chloro-5-methyl-1H-1,2,4-triazole hydrochloride (CAS 1461709-15-8)
- Peptide Impurity 04 (CAS 2913424-91-4)
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