1-(Difluoromethyl)-2,3,4,5,6-pentafluorobenzene CAS 22006-44-6
| CAS No. | 22006-44-6 |
| Molecular Formula | C7HF7 |
| Molecular Weight | 218.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 218.07 g/mol gives 1-(Difluoromethyl)-2,3,4,5,6-pentafluorobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(Difluoromethyl)-2,3,4,5,6-pentafluorobenzene (CAS 22006-44-6) is a high-purity analytical reference standard with the molecular formula C7HF7 and a molecular weight of 218.07 g/mol.
The molecular framework of 1-(Difluoromethyl)-2,3,4,5,6-pentafluorobenzene (C7HF7) is characterized by fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7HF7 |
| Molecular Weight | 218.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-6-hydroxy-5-nitropyridine-3-carboxaldehyde (CAS 1804867-12-6)
- 2-(Difluoromethyl)-5-nitropyridine-4-carboxylic acid (CAS 1805043-83-7)
- 4-(Difluoromethyl)-6-hydroxy-5-nitronicotinaldehyde (CAS 1805068-07-8)
- 2-(Difluoromethyl)-5-hydroxy-4-nitropyridine-3-carboxaldehyde (CAS 1805206-51-2)
- 2-(Difluoromethyl)-5-nitropyridine-3-carboxylic acid (CAS 1805224-32-1)
- 2-(Difluoromethyl)-4-nitropyridine-6-carboxylic acid (CAS 1805313-58-9)
- 4-(Difluoromethyl)-5-nitronicotinic acid (CAS 1805320-12-0)
- 4-(Difluoromethyl)-3-nitropicolinic acid (CAS 1805326-49-1)
Recommended Standards
- 1-(4-Bromo-2-fluorophenyl)-n-methylmethanamine (CAS 887139-06-2)
- 1-Bromo-3-(sulfinylamino)benzene (CAS 89379-48-6)
- 1-(3-Bromophenyl)-2-fluoroethanamine (CAS 929972-40-7)
- 1-Bromo-4-(sulfinylamino)benzene (CAS 26516-62-1)
- CAS 943962-21-8 (CAS 943962-21-8)
- 2-((1H-Benzo[d]imidazol-2-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 41215-89-8)
- (1-(4-Bromophenyl)ethyl)hydrazine (CAS 55294-84-3)
- 5-Bromo-6-methylimidazo[2,1-b][1,3]thiazole (CAS 134670-13-6)
- methyl 1-methyl-5-nitro-1H-indazole-3-carboxylate (CAS 1363380-48-6)
- (S)-2-Amino-N-isopropyl-N-(thiophen-3-ylmethyl)propanamide (CAS 1354010-93-7)
- (2-Chloro-6-(difluoromethoxy)pyridin-4-yl)methanol (CAS 1227586-69-7)
- 2-Bromocyclopent-1-ene-1-carbaldehyde (CAS 89466-25-1)
- 3-Chloro-2-methyl-N-(2-methylphenethyl)aniline (CAS 1040688-34-3)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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