6-Bromo-8-(2-fluorobenzyl)imidazo[1,2-a]pyrazine CAS 2201049-52-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-8-(2-fluorobenzyl)imidazo[1,2-a]pyrazine.

CATO supplies 6-Bromo-8-(2-fluorobenzyl)imidazo[1,2-a]pyrazine (CAS 2201049-52-5), a certified reference material (molecular formula C13H9BrFN3, MW 306.13 g/mol) for analytical method development and quality control.

6-Bromo-8-(2-fluorobenzyl)imidazo[1,2-a]pyrazine (C13H9BrFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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