1-(2,2-Difluoroethyl)-4-piperidin-4-yl-piperazine dihydrochloride CAS 2203952-48-9
| CAS No. | 2203952-48-9 |
| Molecular Formula | C11H21F2N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,2-Difluoroethyl)-4-piperidin-4-yl-piperazine dihydrochloride (CAS 2203952-48-9) is a high-purity analytical reference standard with the molecular formula C11H21F2N3HCl and a molecular weight of 269.76 g/mol.
The molecular framework of 1-(2,2-Difluoroethyl)-4-piperidin-4-yl-piperazine dihydrochloride (C11H21F2N3HCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-4-piperidin-4-yl-piperazine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H21F2N3 2*HCl |
| Molecular Weight | 269.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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- 2-(Aminomethyl)-6-(difluoromethyl)-3-hydroxy-5-methoxypyridine (CAS 1805533-92-9)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
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