(5-Chlorobenzofuran-2-yl)(p-tolyl)methanone CAS 220526-75-0
| CAS No. | 220526-75-0 |
| Molecular Formula | C16H11ClO2 |
| Molecular Weight | 270.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Chlorobenzofuran-2-yl)(p-tolyl)methanone.
(5-Chlorobenzofuran-2-yl)(p-tolyl)methanone (CAS 220526-75-0), molecular formula C16H11ClO2 and molecular weight 270.71 g/mol, is a CATO reference standard with documented purity and traceability.
(5-Chlorobenzofuran-2-yl)(p-tolyl)methanone (C16H11ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClO2 |
| Molecular Weight | 270.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
Related Chlorobenzofuran Standards
- 3-(5-Chlorobenzofuran-2-yl)benzoic acid (CAS 835595-05-6)
- 2-(6-Chlorobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1154741-00-0)
- 2-(6-Chlorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1396751-50-0)
- 6-chlorobenzofuran-3-sulfonyl chloride (CAS 2231234-34-5)
- (5-Chlorobenzofuran-2-yl)(4-methoxyphenyl)methanone (CAS 220526-76-1)
- Ethyl 2-(5-chlorobenzofuran-2-yl)propanoate (CAS 2104363-98-4)
- (5-Chlorobenzofuran-2-yl)(4-chlorophenyl)methanone (CAS 83806-32-0)
- 4-(5-Chlorobenzofuran-2-yl)-1-methylpiperidine (CAS 54403-19-9)
Recommended Standards
- (4-Chloropicolinoyl)-l-leucine (CAS 956438-61-2)
- (E)-2-(4-Chlorobenzylidene)-5-methylbenzofuran-3(2H)-one (CAS 61976-56-5)
- (4-Chlorophenyl)(7-methylimidazo[1,2-a]pyridin-3-yl)methanone (CAS 339103-69-4)
- (E)-3-(2-chloro-4-isopropoxy-5-methoxyphenyl)acrylic acid (CAS 937599-13-8)
- methyl 3-fluoro-4-methoxypyridine-2-carboxylate (CAS 1256819-36-9)
- Triethoxy(propyl)silane (CAS 2550-02-9)
- 3-((2,6-Dichlorophenyl)thio)-N-(2-(phenylthio)ethyl)propanamide (CAS 337923-43-0)
- tert-Butyl (5-nitropyridin-2-yl)carbamate (CAS 161117-88-0)
- Y5DC3IN066 29915-38-6 3-(Tris(hydroxymethyl)methylamino)-1-propanesulfonic acid 1-Propanesulfonic acid, 3-((2-hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)- 3-(Tris(hydroxymethyl)methylamino)propane-1-sulphonic acid EINECS 249-954-1 3-((2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)-1-propanesulfonic acid NSC 610928 UNII-Y5DC3IN066 (CAS 29915-38-6)
- 2-(5-Methoxy-2-methylphenyl)-2-methylpropanoic acid (CAS 29206-05-1)
- 3-Hydroxy-1-(4-methoxyphenyl)cyclobutane-1-carbonitrile (CAS 1481409-11-3)
- 4,4'''-Dibromo-5',5''-bis(4-bromophenyl)-2',2'',4',4'',6',6''-hexamethyl-1,1':3',1'':3'',1'''-quaterphenyl (CAS 1093856-24-6)
- 3-[Isocyano-(toluene-4-sulfonyl)-methyl]-benzoic acid methyl ester (CAS 1008771-33-2)
- Custom peptides (CAS CATO-CPTD788509)
Why CATO?
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