tert-Butyl((4-((5S)-5-((4-fluorophenoxy)methyl)tetrahydrofuran-2-yl)but-3-yn-1-yl)oxy)dimethylsilane CAS 220623-69-8

Purity 97%+In StockPharmaceutical Standards
CAS No.220623-69-8
Molecular FormulaC21H31FO3Si
Molecular Weight378.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl((4-((5S)-5-((4-fluorophenoxy)methyl)tetrahydrofuran-2-yl)but-3-yn-1-yl)oxy)dimethylsilane CAS 220623-69-8 chemical structure

Description

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

tert-Butyl((4-((5S)-5-((4-fluorophenoxy)methyl)tetrahydrofuran-2-yl)but-3-yn-1-yl)oxy)dimethylsilane (CAS 220623-69-8), molecular formula C21H31FO3Si and molecular weight 378.55 g/mol, is a CATO reference standard with documented purity and traceability.

tert-Butyl((4-((5S)-5-((4-fluorophenoxy)methyl)tetrahydrofuran-2-yl)but-3-yn-1-yl)oxy)dimethylsilane (C21H31FO3Si) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H31FO3Si
Molecular Weight378.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2020
Halogen ContentF-containing

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