2-Phenylbenzo[d]isothiazole-3(2H)-thione CAS 22063-61-2
| CAS No. | 22063-61-2 |
| Molecular Formula | C22H37N2O5S3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Phenylbenzo[d]isothiazole-3(2H)-thione (C22H37N2O5S3K) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-Phenylbenzo[d]isothiazole-3(2H)-thione (CAS 22063-61-2), a certified reference material (molecular formula C22H37N2O5S3K, MW 544.82 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Phenylbenzo[d]isothiazole-3(2H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H37N2O5S3 K |
| Molecular Weight | 544.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
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Recommended Standards
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- 2-(Difluoromethyl)-4-nitro-5-(trifluoromethoxy)pyridine-3-carboxaldehyde (CAS 1806772-86-0)
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- 5-Amino-1-methyl-1H-imidazole-4-carbaldehyde (CAS 679800-30-7)
- Amlodipine impurity 68 (CAS 88150-30-5)
- (1E,2E)-N1,N2-Bis(4-methoxyphenyl)ethane-1,2-diimine (CAS 24978-42-5)
- Ethylurethane (CAS 623-78-9)
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Why CATO?
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