2-amino-5-phenoxybenzoic acid CAS 22071-39-2
| CAS No. | 22071-39-2 |
| Molecular Formula | C13H11NO3 |
| Molecular Weight | 229.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-amino-5-phenoxybenzoic acid (CAS 22071-39-2) is a high-purity analytical reference standard with the molecular formula C13H11NO3 and a molecular weight of 229.23 g/mol.
The molecular framework of 2-amino-5-phenoxybenzoic acid (C13H11NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-amino-5-phenoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11NO3 |
| Molecular Weight | 229.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related amino Standards
- 2-Amino-3-phenoxybenzoic acid (CAS 1039878-63-1)
- Methyl3-amino-6-phenylpyridazine-4-carboxylate (CAS 1099794-24-7)
- (S)-2-Amino-3-(4-cyano-1H-indol-3-yl)propanoic acid (CAS 1132749-42-8)
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- 2-(6-Amino-[3,4'-bipyridin]-5-yl)acetic acid (CAS 1227580-16-6)
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Recommended Standards
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- 6-Iodo-1H-indole-2-carboxylic acid (CAS 383133-28-6)
- 7-Chloro-1H-indole-4-carbonitrile (CAS 1167056-48-5)
- 6-Bromo-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-amine (CAS 1823376-15-3)
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