3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one CAS 220749-41-7
| CAS No. | 220749-41-7 |
| Molecular Formula | C17H11ClN2O |
| Molecular Weight | 294.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one (CAS 220749-41-7), molecular formula C17H11ClN2O and molecular weight 294.74 g/mol, is a CATO reference standard with documented purity and traceability.
3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one (C17H11ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((2-Chloro-1H-indol-3-yl)methylene)indolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11ClN2O |
| Molecular Weight | 294.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-((4-Chloro-3,5-dimethylphenoxy)methyl)-1h-pyrazole-3-carbohydrazide (CAS 1004193-92-3)
- 2-Chloro-1,3-bis(1,3-dimethyl-1h-pyrazol-4-yl)propane-1,3-dione (CAS 1006344-26-8)
- 2-Chloro-1,3-bis(1,5-dimethyl-1h-pyrazol-4-yl)propane-1,3-dione (CAS 1006356-88-2)
- 2-Chloro-1-(4-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)ethan-1-one (CAS 1258826-89-9)
- 4-Chloro-8-cycloheptylpteridine-6,7(5H,8H)-dione (CAS 1708401-52-8)
- 1-Benzyl-6-chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 89479-58-3)
- 1-Benzyl-7-chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 89479-60-7)
- 1-Chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile (CAS 849546-10-7)
Recommended Standards
- 2-(5-Chloronaphthalen-1-yl)benzo[d]oxazol-5-amine (CAS 443289-56-3)
- 4-(4-Chlorophenoxy)pyrrolo[1,2-a]quinoxaline (CAS 338401-28-8)
- 2-(5-(4-Chlorophenyl)furan-2-yl)imidazo[1,2-a]pyridine (CAS 53174-13-3)
- 7-Chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinazoline (CAS 57370-21-5)
- Ethyl 1-(5-nitropyridin-2-yl)piperidine-4-carboxylate (CAS 300804-00-6)
- 4-Hydroxy-1-methylcyclohexane-1-carbonitrile (CAS 1501726-52-8)
- (E)-N'-(4-Iodobenzylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2477727-74-3)
- Tert-butyl 4-(3,5-dibromophenyl)piperazine-1-carboxylate (CAS 1121596-44-8)
- (4S,5S)-4,5-Dimethyl-1,3,2-dioxathiolane 2,2-dioxide (CAS 133815-22-2)
- (5-Bromo-4-methylthiazol-2-yl)methanol (CAS 1173897-87-4)
- 7-Bromo-5-chloro-1-benzofuran-2-carboxylic acid (CAS 190775-65-6)
- 2-(5-Bromo-2-methylphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-39-1)
- 4-(4-Fluoro-phenyl)-pyridine 1-oxide (CAS 222551-25-9)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com