Omeprazole Impurity 29 CAS 220757-74-4
| CAS No. | 220757-74-4 |
| Molecular Formula | C16H16ClN3OS |
| Molecular Weight | 333.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Omeprazole Impurity 29 (CAS 220757-74-4), a pharmacopoeial impurity reference standard (molecular formula C16H16ClN3OS, MW 333.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, Omeprazole Impurity 29 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 333.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H16ClN3OS |
| Molecular Weight | 333.84 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Omeprazole Standards
- Omeprazole Sulphide-D3 (CAS 922730-98-1)
- Omeprazole EP Impurity C-d3 (CAS 922731-00-8)
- Omeprazole Impurity 18 (CAS CATO-C4X-125518)
- Omeprazole Impurity 16 (CAS CATO-C4X-125516)
- Omeprazole Impurity 12 (CAS CATO-C4X-125512)
- Omeprazole impurity 34 (CAS CATO-C4X-125534)
- Omeprazole Impurity 26 (CAS 142885-92-5)
- Omeprazole (CAS 73590-58-6)
Recommended Standards
- N-(2-Chlorophenyl)-4-(pyrazin-2-yl)piperazine-1-carbothioamide (CAS 89007-44-3)
- N-Nitroso Chlorpromazine EP Impurity D (CAS 55855-44-2)
- 7-(3-Chlorothiophen-2-yl)-N,N,2,4-tetramethylpyrrolo[1,2-a]pyrimidine-8-carboxamide (CAS 477873-16-8)
- [(4-chlorophenyl)methyl][2-(3,4-diethoxyphenyl)ethyl]amine (CAS 1011399-13-5)
- Piperacillin impurity 98 (CAS CATO-C4X-173298)
- Aspoxicillin Impurity 1 (CAS CATO-C4X-23191)
- Salbutamol Impurity 217 (CAS CATO-C4X-1176217)
- 1,3-Dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 5346-58-7)
- 4-Fluoro-7-methyl-1H-indole-2-carboxamide (CAS 2411760-16-0)
- Treprostinil Impurity 10 (CAS 1911575-29-5)
- 5-methyl-1-[2-(oxan-4-yl)-1,2,3,4-tetrahydroisoquinolin-5-yl]-1H-1,2,3-triazole-4-carboxylic acid hydrochloride (CAS 1315367-05-5)
- 1,4-bis(2-bromoethoxy)benzene (CAS 5471-84-1)
- Methyl 2-(((benzyloxy)carbonyl)(methyl)amino)acetate (CAS 100391-80-8)
- Liraglutide Impurity 6 TFA Salt (CAS CATO-C4X-19926)
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