Methyl 4-amino-2-chlorobenzoate hydrochloride CAS 220848-45-3
| CAS No. | 220848-45-3 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Methyl 4-amino-2-chlorobenzoate hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Methyl 4-amino-2-chlorobenzoate hydrochloride (CAS 220848-45-3) is a high-purity analytical reference standard with the molecular formula C8H8ClNO2HCl and a molecular weight of 222.06 g/mol.
The molecular framework of Methyl 4-amino-2-chlorobenzoate hydrochloride (C8H8ClNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 HCl |
| Molecular Weight | 222.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 3-Amino-1-methyl-4-phenoxyindazole (CAS 1000018-07-4)
- 3-Amino-2,6-dibromo-5-ethoxypyridine (CAS 1000018-10-9)
- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
- Methyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 100002-84-4)
- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
- Methyl 1-amino-4-cyano-1H-pyrrole-2-carboxylate (CAS 1000313-12-1)
- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
- 6-Amino-7-iodo-2,3-dihydro-1H-inden-1-one (CAS 1000333-93-6)
Recommended Standards
- 5-Bromo-3-phenyl-1-(o-tolyl)-1H-pyrazole (CAS 1245126-36-6)
- (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(4-chlorophenyl)prop-2-en-1-one (CAS 338401-30-2)
- 2-amino-1-methyl-1H-1,3-benzodiazole-4-carbonitrile (CAS 1379336-58-9)
- tert-Butyl 4-methyl-2-nitro-1H-indole-1-carboxylate (CAS 1881330-19-3)
- Silverperrhenate (CAS 20654-56-2)
- 5-(Bromomethyl)-2-propylpyrimidine (CAS 1823380-14-8)
- Tandospirone Impurity 9 (CAS 541-59-3)
- 3-Chloro-2-ethoxy-5-fluorobenzaldehyde (CAS 883521-72-0)
- 1-(6-(Indolin-1-yl)-5-methylpyridin-3-yl)propan-1-ol (CAS 1355201-69-2)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com