2-Bromo-4-fluoro-1-methoxy-3-methylbenzene CAS 220901-65-5
| CAS No. | 220901-65-5 |
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-4-fluoro-1-methoxy-3-methylbenzene (CAS 220901-65-5), molecular formula C8H8BrFO and molecular weight 219.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-4-fluoro-1-methoxy-3-methylbenzene (C8H8BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Bromo-4-fluoro-1-methoxy-3-methylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (2-Bromo-5-fluorobenzyl)hydrazine (CAS 1016529-00-2)
- (5-Bromo-2-fluorobenzyl)hydrazine (CAS 1016699-41-4)
- (1s)-1-(4-Bromo-2-fluorophenyl)ethan-1-ol (CAS 1026088-11-8)
- 1-Bromo-4-ethoxy-2-fluorobenzene (CAS 107713-66-6)
- (R)-2-Bromo-1-(4-fluorophenyl)ethanol (CAS 1097211-38-5)
- 4-bromo-1-ethoxy-2-fluorobenzene (CAS 115467-08-8)
- (S)-2-Bromo-1-(3-fluorophenyl)ethan-1-ol (CAS 1176484-68-6)
- 5-Bromo-2-fluoro-3-methylbenzyl alcohol (CAS 1197944-22-1)
Recommended Standards
- 2-Bromo-1-fluoro-4-(methoxymethyl)benzene (CAS 887268-22-6)
- 2-Bromo-5-fluoro-4-methylanisole (CAS 314298-15-2)
- 2-Bromo-1-ethoxy-4-fluorobenzene (CAS 326-69-2)
- 2-Bromo-6-(2-fluoropropan-2-yl)pyrazine (CAS 2673371-80-5)
- Methyl 4-fluoro-5-formyl-2-methoxybenzoate (CAS 2167657-25-0)
- 2,6-Difluoro-4-(trifluoromethyl)aniline (CAS 123950-45-8)
- 1-(3-Iodo-5-(trifluoromethyl)phenyl)ethan-1-one (CAS 1393557-53-3)
- N-(3,5-dimethylphenyl)-N-(methylsulfonyl)glycine (CAS 353502-16-6)
- 3-Hydroxy-5,6,7,8-tetrahydro-10-oxa-8-aza-benzo[a]azulen-9-one (CAS 521937-07-5)
- Sitstanol-5,6,22,23-d<SUB>4</SUB> (CAS 150044-25-0)
- 1,4-Bis(propan-2-yl)-1,4,7-triazonane (CAS 169833-92-5)
- 8-(3-Bromo-4-methylphenyl)-8-oxooctanoic acid (CAS 898767-25-4)
- tert-Butyl (4-benzylpiperidin-4-yl)methylcarbamate (CAS 1707602-65-0)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com