2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride CAS 220987-96-2

Purity 97%+In StockPharmaceutical Standards
CAS No.220987-96-2
Molecular FormulaC6BrClF4O2S
Molecular Weight327.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride CAS 220987-96-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride.

2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride (CAS 220987-96-2), molecular formula C6BrClF4O2S and molecular weight 327.48 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system, 2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Bromo-3,4,5,6-tetrafluorobenzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6BrClF4O2S
Molecular Weight327.48 g/mol
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2020
Halogen ContentF/Cl/Br-containing
Sulfur Atoms1

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