Nemonoxacin impurity 103 CAS 221221-13-2
| CAS No. | 221221-13-2 |
| Molecular Formula | C16H17F2NO4 |
| Molecular Weight | 325.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nemonoxacin impurity 103.
CATO supplies Nemonoxacin impurity 103 (CAS 221221-13-2), a pharmacopoeial impurity reference standard (molecular formula C16H17F2NO4, MW 325.31 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nemonoxacin impurity 103 (C16H17F2NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nemonoxacin impurity 103 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H17F2NO4 |
| Molecular Weight | 325.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nemonoxacin Standards
- Nemonoxacin Impurity 23 (CAS CATO-C4X-312823)
- Nemonoxacin Impurity 32 (CAS CATO-C4X-312832)
- Nemonoxacin impurity 48 (CAS CATO-C4X-312848)
- Nemonoxacin impurity 49 (CAS CATO-C4X-312849)
- Nemonoxacin Impurity 36 (CAS CATO-C4X-312836)
- Nemonoxacin Impurity 100 (CAS CATO-C4X-3128100)
- Nemonoxacin impurity 105 (CAS 656234-57-0)
- Nemonoxacin Impurity 24 (CAS CATO-C4X-312824)
Recommended Standards
- Isavuconazole Impurity 159 (CAS CATO-C4X-1236159)
- Baclofen Impurity 57 (CAS CATO-C4X-101257)
- (2E,4E)-2-Cyano-5-{[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]amino}-3-methylhexa-2,4-dienoic acid (CAS 1020241-30-8)
- N1-(2,4-Difluorophenyl)-N2-(3-(2-oxopyrrolidin-1-yl)propyl)oxalamide (CAS 898357-10-3)
- Cariprazine Impurity 54 (CAS CATO-C4X-240854)
- Doxapram Impurity 28 (CAS CATO-C4X-197328)
- Cefotaxime Impurity 84 (CAS CATO-C4X-120184)
- Avibactam Impurity 69 (CAS CATO-C4X-134869)
- 3,4-Dibromotetrahydrothiophene 1,1-dioxide (CAS 15091-30-2)
- Dimethyl 3-[2-(Ethylsulfonyl)propyl]glutarate (CAS 116007-16-0)
- 1-(3-Chlorophenyl)-1,2,3,4-tetrahydroisoquinoline (CAS 774120-07-9)
- 1-(3-(Trifluoromethyl)phenyl)-1h-pyrazol-5-amine (CAS 78119-07-0)
- (E)-N'-(5-cyanopyrimidin-2-yl)-N-methoxyformimidamide (CAS 400085-18-9)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com