1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one CAS 22136-54-5
| CAS No. | 22136-54-5 |
| Molecular Formula | C21H17NO |
| Molecular Weight | 299.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one (CAS 22136-54-5) is a high-purity analytical reference standard with the molecular formula C21H17NO and a molecular weight of 299.37 g/mol.
1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one (C21H17NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17NO |
| Molecular Weight | 299.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-(Difluoromethyl)-3-hydroxy-4-methylpyridine-6-methanol (CAS 1805452-01-0)
- 2,4,6-Trimethyl-N,N-diphenylaniline (CAS 603134-65-2)
- Bupivacaine Impurity 13 (CAS 51989-48-1)
- Sildenafil Impurity 299 (CAS CATO-C4X-1128299)
- Ethyl 4-(4-cyanophenyl)butanoate (CAS 131379-33-4)
- 1-(3,4-dihydro-2H-pyran-5-yl)ethan-1-one (CAS 67496-35-9)
- Ethyl 2-{6-oxo-3-[(E)-2-phenylethenyl]-1,6-dihydropyridazin-1-yl}propanoate (CAS 1164486-00-3)
- Palmitoyl Pentapeptide-4 (CAS 214047-00-4)
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