5,6-Dibromo-1,1,3,3-tetramethylisoindoline CAS 221368-76-9
| CAS No. | 221368-76-9 |
| Molecular Formula | C12H15Br2N |
| Molecular Weight | 333.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,6-Dibromo-1,1,3,3-tetramethylisoindoline (CAS 221368-76-9), molecular formula C12H15Br2N and molecular weight 333.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5,6-Dibromo-1,1,3,3-tetramethylisoindoline (C12H15Br2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,6-Dibromo-1,1,3,3-tetramethylisoindoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15Br2N |
| Molecular Weight | 333.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Dibromo Standards
- 2,6-Dibromo-4-cyclohexylaniline (CAS 175135-11-2)
- 3,4-Dibromo-1,4-dimethyl-3,4-dihydroquinolin-2(1H)-one (CAS 91066-08-9)
- 2-(4,5-Dibromo-1H-indol-3-yl)acetic acid (CAS 1227502-38-6)
- 2-(4,7-Dibromo-1H-indol-3-yl)acetic acid (CAS 1227572-01-1)
- 2-(4,6-Dibromo-1H-indol-3-yl)acetic acid (CAS 1227581-93-2)
- Methyl 5,6-dibromo-1H-indole-3-carboxylate (CAS 1309792-72-0)
- Methyl 3,4-dibromo-1H-indole-6-carboxylate (CAS 1352394-97-8)
- Methyl 2-(3,5-dibromo-4-cyanophenyl)acetate (CAS 1804892-46-3)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(3-nitro-4-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane (CAS 2096336-45-5)
- 1-(2,6-Dibromobenzyl)piperidine (CAS 1414870-72-6)
- 13C6-Niclosamide hydrate (CAS 1325559-12-3)
- 8-Fluoro-4-hydroxy-6-iodoquinoline-3-carboxylic acid (CAS 228728-29-8)
- 2-Chloro-N-(2-((2-cyano-4-nitrophenyl)diazenyl)-5-(diethylamino)phenyl)acetamide (CAS 64294-88-8)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-N-methyl-6-[(phenylsulfanyl)methyl]pyrimidin-4-amine (CAS 341965-39-7)
- 3,4-Bis(Hydroxymethyl)thiophene (CAS 18354-73-9)
- Methyl 2-(4-bromo-1h-pyrazol-1-yl)propanoate (CAS 1005566-07-3)
- 2-(Chloromethyl)-3,5-dimethylpyridine 1-oxide (CAS 153476-70-1)
- Methyl 3-(4-amino-2-methylphenoxy)benzoate (CAS 946785-17-7)
- N-((4-bromothiophen-2-yl)methyl)-3-methylcyclohexan-1-amine (CAS 1096310-69-8)
- 3-(3-Methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine (CAS 796067-53-3)
- 2-Bromo-5-(4-fluorophenyl)thiazole-4-carboxylic acid (CAS 1137129-05-5)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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