(R)-2-Hydroxy-3,3-dimethylbutanoic acid CAS 22146-57-2
| CAS No. | 22146-57-2 |
| Molecular Formula | C6H12O3 |
| Molecular Weight | 132.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(R)-2-Hydroxy-3,3-dimethylbutanoic acid (CAS 22146-57-2), molecular formula C6H12O3 and molecular weight 132.16 g/mol, is a CATO reference standard with documented purity and traceability.
(R)-2-Hydroxy-3,3-dimethylbutanoic acid (C6H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions.
As a certified reference material (CRM), (R)-2-Hydroxy-3,3-dimethylbutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12O3 |
| Molecular Weight | 132.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1963 |
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Recommended Standards
- (R)-2-Amino-3-(dimethylamino)propanoic acid (CAS 206559-98-0)
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- (R)-2-methoxy-2-methylbutanoic acid (CAS 55394-68-8)
- 2-(4-(Difluoromethyl)-5-fluoro-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1806021-47-5)
- Di-tert-butyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate (CAS 910628-19-2)
- Sodium ((4-aminophenyl)sulfonyl)amide (CAS 10103-15-8)
- 8-hydroxy-5-azaspiro[3.5]nonan-6-one (CAS 1909336-23-7)
- 3-((Dicyclopropylmethyl)amino)propan-1-ol (CAS 1099051-70-3)
- 2,3,5,6-Tetramethylbenzoyl chloride (CAS 67075-69-8)
- 3-Amino-5-methoxypicolinic acid (CAS 1393585-04-0)
- Methyl 4-fluoro-3-hydroxy-1H-indole-2-carboxylate (CAS 190433-37-5)
- 2-(3-Bromophenyl)-1-(3-(trifluoromethyl)phenyl)ethan-1-one (CAS 898784-20-8)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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