Etoricoxib Impurity 6 CAS 221615-75-4
| CAS No. | 221615-75-4 |
| Molecular Formula | C15H15NO3S |
| Molecular Weight | 289.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Etoricoxib Impurity 6 (CAS 221615-75-4), a pharmacopoeial impurity reference standard (molecular formula C15H15NO3S, MW 289.35 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Etoricoxib Impurity 6 (C15H15NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Etoricoxib Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H15NO3S |
| Molecular Weight | 289.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 29 (CAS 1798110-01-6)
- Etoricoxib Impurity 38 (CAS CATO-C4X-108038)
- Etoricoxib Impurity 41 (CAS 60891-70-5)
- Etoricoxib Impurity 20 (CAS CATO-C4X-108020)
- Etoricoxib impurity 67 (CAS 859824-65-0)
- Etoricoxib Impurity 35 (CAS 40061-50-5)
- Etoricoxib Impurity 23 (CAS 1810761-43-3)
- Etoricoxib Impurity 91 (CAS CATO-C4X-108091)
Recommended Standards
- Pitavastatin Impurity 55 (CAS 1187966-94-4)
- Pefloxacin Mesilate Dihydrate EP Impurity E (CAS 879005-96-6)
- tert-butyl N-(7-fluoro-3-hydroxy-1,5-naphthyridin-2-yl)carbamate (CAS 2435612-65-8)
- Amonafide-d6 (CAS 1217039-92-3)
- Relugolix Impurity 102 (CAS CATO-C4X-2429102)
- Midazolam Impurity 16 (CAS 59467-64-0)
- Aminolevulinic Acid Impurity 7 (CAS CATO-C4X-21217)
- 3-Benzylcyclopent-2-en-1-one (CAS 67100-39-4)
- Ethyl 4-(3,4-dimethylphenyl)-4-oxobutyrate (CAS 175394-01-1)
- Chlorprothixene EP Impurity D Oxalate (CAS 1082649-26-0（free base）)
- (2-Bromo-6-chloropyridin-3-yl)methanol (CAS 1227589-11-8)
- Potassium (3-fluoro-4-formylphenyl)trifluoroborate (CAS 1451390-71-8)
- 1-amino-3-bromo-1H-pyrrole-2-carboxamide (CAS 1548339-16-7)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com