(1r,3R,5s)-8-azaspiro[bicyclo[3.2.1]octane-3,3'-indoline]hydrochloride CAS 2216750-94-4
| CAS No. | 2216750-94-4 |
| Molecular Formula | C14H18N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 250.77 g/mol gives (1r,3R,5s)-8-azaspiro[bicyclo[3.2.1]octane-3,3'-indoline]hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(1r,3R,5s)-8-azaspiro[bicyclo[3.2.1]octane-3,3'-indoline]hydrochloride (CAS 2216750-94-4), molecular formula C14H18N2HCl and molecular weight 250.77 g/mol, is a CATO reference standard with documented purity and traceability.
(1r,3R,5s)-8-azaspiro[bicyclo[3.2.1]octane-3,3'-indoline]hydrochloride (C14H18N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (1r,3R,5s)-8-azaspiro[bicyclo[3.2.1]octane-3,3'-indoline]hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18N2 HCl |
| Molecular Weight | 250.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N10,N10,N10',N10'-Tetraphenyl-[9,9'-bianthracene]-10,10'-diamine (CAS 220721-68-6)
- 2-Chloro-4-fluoro-4-(4-methylpiperazinomethyl) benzophenone (CAS 898783-99-8)
- 4-Chloro-N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethyl)benzamide (CAS 338792-82-8)
- Tert-butyl 2-amino-6-methyl-4h,5h,6h,7h-thieno[2,3-c]pyridine-3-carboxylate (CAS 353467-24-0)
- Phosdiphen (CAS 36519-00-3)
- 6-Fluoro-3,5-diiodopyridin-2-amine (CAS 1402148-90-6)
- 2,2,3,3-Tetrafluorosuccinamide (CAS 377-37-7)
- UBMOF-8 (CAS 2022220-48-8)
- Pazopanib Impurity 21 (CAS 6269-91-6)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
Why CATO?
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