2-(Chloromethyl)-4,6-dimethylpyridine hydrochloride CAS 221904-15-0
| CAS No. | 221904-15-0 |
| Molecular Formula | C8H10ClN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(Chloromethyl)-4,6-dimethylpyridine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-(Chloromethyl)-4,6-dimethylpyridine hydrochloride (CAS 221904-15-0) is a high-purity analytical reference standard with the molecular formula C8H10ClNHCl and a molecular weight of 192.08 g/mol.
The molecular framework of 2-(Chloromethyl)-4,6-dimethylpyridine hydrochloride (C8H10ClNHCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN HCl |
| Molecular Weight | 192.08 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
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Recommended Standards
- 6-Chloroisoindolin-1-one (CAS 58083-59-3)
- [(2,6-difluorophenyl)methyl][(1,3-thiazol-2-yl)methyl]amine (CAS 1247992-83-1)
- 4,6-Dichloro-n,n,5-trimethylpyrimidin-2-amine (CAS 61770-00-1)
- Indoleacetic Acid-13C6 (CAS 100849-36-3)
- N-[2-(3-Bromophenyl)ethyl]-N-methylamine (CAS 785032-26-0)
- Imrecoxib Impurity 58 (CAS CATO-C4X-237958)
- 4-chloro-2-methylnaphthalen-1-amine (CAS 341028-97-5)
- 4-((4-Amino-3-chlorophenyl)thio)benzonitrile (CAS 1360607-85-7)
- 3-Hydrazino-1-methylquinoxalin-2(1H)-one (CAS 31595-64-9)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com