1,1,1-Trifluoro-4-(4-methoxyphenyl)butan-2-one CAS 221915-87-3

Description

The occurrence of 1,1,1-Trifluoro-4-(4-methoxyphenyl)butan-2-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1,1,1-Trifluoro-4-(4-methoxyphenyl)butan-2-one (CAS 221915-87-3) is a high-purity analytical reference standard with the molecular formula C11H11F3O2 and a molecular weight of 232.20 g/mol.

The molecular framework of 1,1,1-Trifluoro-4-(4-methoxyphenyl)butan-2-one (C11H11F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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