Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate CAS 2219378-63-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2219378-63-7
Molecular FormulaC13H22FNO3
Molecular Weight259.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate CAS 2219378-63-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate.

CATO supplies Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate (CAS 2219378-63-7), a certified reference material (molecular formula C13H22FNO3, MW 259.32 g/mol) for analytical method development and quality control.

Structurally, Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate (C13H22FNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 259.32 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Tert-butyl 8-fluoro-8-(hydroxymethyl)-6-azaspiro[3.4]Octane-6-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H22FNO3
Molecular Weight259.32 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

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