Ethyl 7-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate CAS 22200-48-2
| CAS No. | 22200-48-2 |
| Molecular Formula | C12H10INO3 |
| Molecular Weight | 343.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Ethyl 7-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 22200-48-2), a certified reference material (molecular formula C12H10INO3, MW 343.12 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 7-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (C12H10INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10INO3 |
| Molecular Weight | 343.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 3-iodo-2-methyl-4-oxo-1,4-dihydroquinoline-8-carboxylate (CAS 1330750-90-7)
- Methyl 3-iodo-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxylate (CAS 1330755-65-1)
- 1-Acetyl-5-iodo-1H-indol-3-yl acetate (CAS 26490-98-2)
- ethyl 6-iodo-4-oxo-1,4-dihydro-3-quinolinecarboxylate (CAS 302949-01-5)
- Ethyl 8-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 205597-70-2)
- Methyl 3-iodo-8-methoxyquinoline-6-carboxylate (CAS 2639207-63-7)
- Methyl 4-iodo-3-methoxyquinoline-7-carboxylate (CAS 2866497-98-3)
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Recommended Standards
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- N-Hydroxy-2-((5-iodoquinolin-8-yl)oxy)acetimidamide (CAS 88757-36-2)
- [1-(2-phenylethyl)pyrrolidin-3-yl]methanol (CAS 2148-52-9)
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- 7-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1547041-34-8)
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- N-((4aR,6R,7R,8R,8aS)-6,8-Bis(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide (CAS 14040-20-1)
- 1-Methyl-4-(pyridin-3-ylmethyl)piperazine (CAS 414887-76-6)
- trans-4-chloro-1,1-dioxo-thiolan-3-amine (CAS 769883-23-0)
- 2-Hydroxy-3-phenyl-6-(trifluoromethyl)pyridine (CAS 1214353-50-0)
- 2-(Furan-2-yl)-6-nitroimidazo[1,2-a]pyridine (CAS 904818-21-9)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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