4-Phenylpyrimidine-2-carbonitrile CAS 22220-27-5
| CAS No. | 22220-27-5 |
| Molecular Formula | C11H7N3 |
| Molecular Weight | 181.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Phenylpyrimidine-2-carbonitrile (CAS 22220-27-5), molecular formula C11H7N3 and molecular weight 181.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Phenylpyrimidine-2-carbonitrile (C11H7N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Phenylpyrimidine-2-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7N3 |
| Molecular Weight | 181.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
Related Phenylpyrimidine Standards
- 2-Phenylpyrimidine-4-carbonitrile (CAS 83858-04-2)
- 2-phenylpyrimidine-5-carbonitrile (CAS 85386-15-8)
- 5-Phenylpyrimidine-2-carbonitrile (CAS 85386-18-1)
- 6-Phenylpyrimidine-4-carbonitrile (CAS 83858-06-4)
- 2-Phenylpyrimidine-4-carbaldehyde (CAS 1014-07-9)
- 5-Phenylpyrimidine-2-carbaldehyde (CAS 1261753-52-9)
- 2-Phenylpyrimidine-5-carbaldehyde (CAS 130161-46-5)
- 2-Ethyl-4-phenylpyrimidine (CAS 91391-86-5)
Recommended Standards
- 4-NITRO-2,3,5-TRIMETHYLPHENOL (CAS 92892-04-1)
- 5-(2-Amino-ethyl)-2-hydroxy-benzoic acid (CAS 4900-26-9)
- 4-Isopropoxypicolinic acid (CAS 863507-74-8)
- 5-(2-Hydroxypropan-2-yl)picolinic acid (CAS 2068151-91-5)
- Ethyl 8-(2,3-difluorophenyl)-8-oxooctanoate (CAS 898753-04-3)
- 1-Cyclohexyl-N,N'-diethyl-1-methylsilanediamine (CAS 1352486-81-7)
- 5-Hydroxy-3-[3-(trifluoromethyl)phenyl]isoxazole (CAS 1354930-06-5)
- 2-(Azetidin-3-yloxy)-3-chloropyridine hydrochloride (CAS 2098098-63-4)
- 2-Iodoisonicotinic acid (CAS 58481-10-0)
- 2-(8-(Cyclohexylamino)-3-methyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid (CAS 115398-45-3)
- 8-Fluoro-5-methoxy-1,2,3,4-tetrahydronaphthalen-1-one (CAS 49800-59-1)
- Urolithin M7 (CAS 531512-26-2)
- 1-(2-Naphthyl)piperazine dihydrochloride (CAS 57536-91-1)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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