tert-Butyl ((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)carbamate CAS 2222114-19-2
| CAS No. | 2222114-19-2 |
| Molecular Formula | C18H23ClN2O3 |
| Molecular Weight | 350.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl ((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)carbamate (CAS 2222114-19-2), molecular formula C18H23ClN2O3 and molecular weight 350.84 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, tert-Butyl ((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)carbamate (C18H23ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 350.84 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl ((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H23ClN2O3 |
| Molecular Weight | 350.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 8-Chloro-4,4,5-trimethyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-35-2)
- tert-Butyl ((1s,4s)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)carbamate (CAS 2222118-97-8)
- 5-Chloro-3-ethyl-3-methyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-18-1)
- Tert-butyl 4-(6-chloro-2-oxoindolin-3-yl)piperidine-1-carboxylate (CAS 917917-50-1)
- 1-(2,4-Dinitrophenyl)-piperazine hydrochloride (CAS 125422-00-6)
- 6,7-Dimethoxy-3,4-dihydroisoquinolin-1(2H)-one (CAS 493-49-2)
- 1H-Benzo[d][1,2,3]triazol-4-amine hydrochloride (CAS 4331-30-0)
- N-(3,5-Bis(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618415-07-9)
- N-(Cyclopentylmethyl)hydrazine dihydrochloride (CAS 1172489-30-3)
- 5-(3-Aminopropyl)-1,2,4-Triazole (CAS 616197-93-4)
- 1,4-Bis(ethylamino)-5,8-dihydroxyanthracene-9,10-dione (CAS 100495-56-5)
- Pazopanib Impurity 54 (CAS CATO-C4X-172554)
- (2E)-3-(2H-1,3-Benzodioxol-5-yl)-N-(4-phenoxyphenyl)prop-2-enamide (CAS 298215-73-3)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com