1-(1,1,1-Trifluoropropan-2-yl)piperidin-4-amine dihydrochloride CAS 2222518-34-3
| CAS No. | 2222518-34-3 |
| Molecular Formula | C8H15F3N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(1,1,1-Trifluoropropan-2-yl)piperidin-4-amine dihydrochloride (C8H15F3N2HCl) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1-(1,1,1-Trifluoropropan-2-yl)piperidin-4-amine dihydrochloride (CAS 2222518-34-3), a certified reference material (molecular formula C8H15F3N2HCl, MW 232.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H15F3N2 2*HCl |
| Molecular Weight | 232.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Trifluoropropan Standards
- N-(1,1,1-Trifluoropropan-2-yl)benzamide (CAS 112738-53-1)
- 4-(1,1,1-trifluoropropan-2-yl)benzoic acid (CAS 1147531-37-0)
- 1,1,1-Trifluoropropan-2-yl indolizine-3-carboxylate (CAS 115974-04-4)
- 1,1,1-Trifluoropropan-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate (CAS 118334-94-4)
- (1,1,1-Trifluoropropan-2-yl)hydrazine (CAS 118737-68-1)
- (S)-1,1,1-Trifluoropropan-2-amine (CAS 125278-10-6)
- 1,1,1-Trifluoropropan-2-yl carbonochloridate (CAS 136205-25-9)
- 4-(1,1,1-Trifluoropropan-2-yl)pyrimidine-5-carbonitrile (CAS 1427195-03-6)
Recommended Standards
- 2-(Allyloxy)-1,3-dimethoxybenzene (CAS 5438-54-0)
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- Methyl 4-fluoro-1-methyl-5-(phenylamino)-1H-benzo[d]imidazole-6-carboxylate (CAS 1415564-48-5)
- 1-(2,4-Bis(benzyloxy)-5-isopropylphenyl)ethanone (CAS 747414-18-2)
- 3-Chloro-3-ethylhexane (CAS 116530-76-8)
- methyl (3R)-3-fluoropyrrolidine-3-carboxylate hydrochloride (CAS 2306253-52-9)
- 5-Azaspiro[3.4]octan-7-ol hydrochloride (CAS 2247102-02-7)
- 2-(Difluoromethyl)-7-methylbenzo[d]oxazole (CAS 1806319-99-2)
- Methyl (1S)-2-azabicyclo[3.1.0]Hexane-1-carboxylate (CAS 1221825-05-3)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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