N1,N3-Bis(2-carbamoylphenyl)isophthalamide CAS 22228-51-9
| CAS No. | 22228-51-9 |
| Molecular Formula | C22H18N4O4 |
| Molecular Weight | 402.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N1,N3-Bis(2-carbamoylphenyl)isophthalamide.
N1,N3-Bis(2-carbamoylphenyl)isophthalamide (CAS 22228-51-9), molecular formula C22H18N4O4 and molecular weight 402.40 g/mol, is a CATO reference standard with documented purity and traceability.
N1,N3-Bis(2-carbamoylphenyl)isophthalamide (C22H18N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N1,N3-Bis(2-carbamoylphenyl)isophthalamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18N4O4 |
| Molecular Weight | 402.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
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