3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-chlorophenyl)thiazol-5-yl)boronate CAS 2223044-67-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2223044-67-3
Molecular FormulaC15H19BClNO3S
Molecular Weight339.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-chlorophenyl)thiazol-5-yl)boronate CAS 2223044-67-3 chemical structure

Description

CATO supplies 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-chlorophenyl)thiazol-5-yl)boronate (CAS 2223044-67-3), a certified reference material (molecular formula C15H19BClNO3S, MW 339.65 g/mol) for analytical method development and quality control.

The molecular framework of 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-chlorophenyl)thiazol-5-yl)boronate (C15H19BClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H19BClNO3S
Molecular Weight339.65 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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