5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-8-amine CAS 2223046-91-9
| CAS No. | 2223046-91-9 |
| Molecular Formula | C15H19BN2O2 |
| Molecular Weight | 270.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-8-amine (CAS 2223046-91-9), a certified reference material (molecular formula C15H19BN2O2, MW 270.13 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-8-amine (C15H19BN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-8-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19BN2O2 |
| Molecular Weight | 270.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Related Tetramethyl Standards
- 1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1002334-12-4)
- 3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole (CAS 1196879-97-6)
- 6-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline (CAS 1210047-61-2)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-amine (CAS 1210048-27-3)
- 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1h-pyrazole (CAS 1217340-87-8)
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazole (CAS 1229584-17-1)
- 1-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole (CAS 1233146-06-9)
- 4,4,5,5-Tetramethyl-2-(4-phenylfuran-2-yl)-1,3,2-dioxaborolane (CAS 1242517-60-7)
Recommended Standards
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indoline-7-carbonitrile (CAS 2103386-39-4)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-ol (CAS 944801-71-2)
- 4-Benzyloxy-2-isopropylphenylboronic acid (CAS 211495-36-2)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2323577-75-7)
- tert-Butyl (S)-3-((pyridin-4-ylmethyl)amino)piperidine-1-carboxylate (CAS 1217722-00-3)
- 1-(3-Hydroxypiperidin-1-yl)-2-(thiophen-3-yl)ethanone (CAS 916791-32-7)
- 2-Propenamide, 3-(3-hydroxy-4-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-[4-[(1E)-3-[[2-(4-hydroxyphenyl)ethyl]amino]-3-oxo-1-propen-1-yl]-2-methoxyphenoxy]-, (2Z)- (CAS 1374216-67-7)
- (2E)-3-Oxo-N-(pyrimidin-2-yl)-2-{[(pyrimidin-2-yl)amino]methylidene}butanamide (CAS 338406-52-3)
- (S)-1-((S)-2-amino-3,3-dimethylbutanoyl)-N-(4-iodophenyl)-N-phenylpyrrolidine-2-carboxamide (CAS 371919-42-5)
- 1H-pyrrolo[3,2-h]quinoline-3-carboxylic acid (CAS 67509-88-0)
- 6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1538113-30-2)
- Bis(4-(chlorocarbonyl)phenyl) nonanedioate compound with 4,4'-((2,2,3,3,4,4,5,5-octafluorohexane-1,6-diyl)bis(oxy))dianiline (1:1) (CAS 124741-20-4)
- Methyl 1-bromo-2-naphthoate (CAS 89555-39-5)
- Renin Inhibitor Peptide (CAS 50410-01-0)
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