Dimethyl (2S,3S)-2,3-Difluorosuccinate CAS 222312-03-0
| CAS No. | 222312-03-0 |
| Molecular Formula | C6H8F2O4 |
| Molecular Weight | 182.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dimethyl (2S,3S)-2,3-Difluorosuccinate.
CATO supplies Dimethyl (2S,3S)-2,3-Difluorosuccinate (CAS 222312-03-0), a certified reference material (molecular formula C6H8F2O4, MW 182.12 g/mol) for analytical method development and quality control.
The molecular framework of Dimethyl (2S,3S)-2,3-Difluorosuccinate (C6H8F2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O4 |
| Molecular Weight | 182.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F-containing |
Related Dimethyl Standards
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Recommended Standards
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- 1-((4-Ethoxyphenyl)amino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione (CAS 303225-49-2)
- 4'-Chloro-3-hydroxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 343603-96-3)
- (S)-Methyl 3-amino-2-hydroxypropanoate (CAS 133153-75-0)
- n-(1-(4-Bromophenyl)ethyl)-3-methylisoxazole-5-carboxamide (CAS 1099720-60-1)
- N,N-Bis(1-methylethyl)dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (CAS 879083-07-5)
- N-(5-amino-2-chlorophenyl)nicotinamide (CAS 937392-56-8)
- 1-Phenyl-2-selenoxo-1,2-dihydropyridine-3-carbaldehyde (CAS 65823-99-6)
- 5-Chloro-2-methoxy-3-methylpyridin-4-amine (CAS 2450343-15-2)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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