4-(trifluoromethyl)pyridine-2-carboxamide CAS 22245-87-0
| CAS No. | 22245-87-0 |
| Molecular Formula | C7H11F3N2O |
| Molecular Weight | 196.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(trifluoromethyl)pyridine-2-carboxamide is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(trifluoromethyl)pyridine-2-carboxamide (CAS 22245-87-0) is a high-purity analytical reference standard with the molecular formula C7H11F3N2O and a molecular weight of 196.17 g/mol.
4-(trifluoromethyl)pyridine-2-carboxamide (C7H11F3N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11F3N2O |
| Molecular Weight | 196.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- Ethyl 1-(trifluoromethyl)cyclobutane-1-carboxylate (CAS 1040683-08-6)
- 3-(Trifluoromethyl)cyclohexane-1-carboxylic Acid (CAS 104907-44-0)
- 1-[5-(trifluoromethyl)pyrazin-2-yl]ethanone (CAS 1060812-68-1)
- 6-(trifluoromethyl)piperidine-3-carboxamide (CAS 1155103-12-0)
- cis-4-(Trifluoromethyl)cyclohexanecarboxylic acid (CAS 1202578-27-5)
- Ethyl 2-(trifluoromethyl)cyclobutane-1-carboxylate (CAS 1256483-62-1)
- trans-4-(Trifluoromethyl)cyclohexanecarboxylic Acid (CAS 133261-33-3)
- 1-[2-(trifluoromethyl)pyrimidin-5-yl]ethanone (CAS 1367970-52-2)
Recommended Standards
- 4-(Trifluoromethoxy)cyclohexanecarbaldehyde (CAS 2231673-69-9)
- Methyl 2-deoxy-2-fluoro-b-D-glucopyranoside (CAS 39110-58-2)
- 3-Fluoro-5-(trifluoromethyl)benzenethiol (CAS 917246-23-2)
- Methyl 2-fluoro-3,3,3-trimethoxypropanoate (CAS 77778-66-6)
- 4-Ethoxy-3-(trifluoromethyl)benzenesulfonyl chloride (CAS 1706446-86-7)
- 5-Aminoallyl-2-deoxyuridine (CAS 87980-17-4)
- [5-(4-chlorophenyl)-4-methyl-1,3-oxazol-2-yl]methanamine (CAS 1226210-63-4)
- 5-Bromo-4,6-dichloro-2-((methylsulfonyl)methyl)pyrimidine (CAS 1423024-74-1)
- 5-(2-Bromophenyl)furan-2-carbaldehyde (CAS 58110-57-9)
- 4-(Difluoromethyl)-6-methoxy-5-methylnicotinamide (CAS 1806862-68-9)
- 6-Amino-4-oxo-4H-chromene-3-carbaldehyde (CAS 1320360-41-5)
- 2-(3-Chlorophenyl)-1-methylpiperidine-3-carboxylic acid (CAS 1315367-70-4)
- (2R,3R,4R,5S)-6-(2-Phenylhydrazono)hexane-1,2,3,4,5-pentaol (CAS 3713-25-5)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
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