7-Nitro-3,4-dihydroquinolin-2(1H)-one CAS 22246-10-2
| CAS No. | 22246-10-2 |
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Nitro-3,4-dihydroquinolin-2(1H)-one.
CATO supplies 7-Nitro-3,4-dihydroquinolin-2(1H)-one (CAS 22246-10-2), a certified reference material (molecular formula C9H8N2O3, MW 192.17 g/mol) for analytical method development and quality control.
7-Nitro-3,4-dihydroquinolin-2(1H)-one (C9H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 6-Methyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-22-6)
- 6-Methyl-3-nitro-1H-pyrrolo[2,3-b]pyridin-5-amine (CAS 1000340-23-7)
- 7-Nitro-1,2,3,4-tetrahydroquinolin-4-one (CAS 114417-33-3)
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- 5-Nitro-3,4-dihydroisoquinolin-1(2H)-one (CAS 135329-21-4)
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Recommended Standards
- 7-Nitro-3,4-dihydroisoquinolin-1(2H)-one (CAS 22245-96-1)
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- 7-Methoxyisochroman-1,3-dione (CAS 4702-29-8)
- 8-Hydroxy-2h-chromene-3-carboxylic acid (CAS 923215-10-5)
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- 2-(4-Iodobenzoyl)benzonitrile (CAS 890098-79-0)
- 1-(3,5-Dimethylbenzyl)-1h-1,2,4-triazol-3-amine (CAS 1183533-61-0)
- (2R,3R)-3,4-Dihydro-3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-2H-1-benzopyran-5-yl Hydrogen Sulfate (CAS 1373035-55-2)
- ((Allyloxy)carbonyl)-L-valyl-L-alanine (CAS 330970-70-2)
- 2-Bromo-5-(cyclopropylsulfamoyl)benzoic acid (CAS 852933-48-3)
- 5-Cyclopropylpyrazin-2-ol (CAS 1159817-53-4)
- 2-(3-(1H-Pyrazol-4-yl)phenyl)acetonitrile (CAS 857531-33-0)
- 4-((2,6-Dichlorophenoxy)methyl)-1-phenyl-1H-1,2,3-triazole (CAS 135034-74-1)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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