8-Hydroxy-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one CAS 22246-84-0
| CAS No. | 22246-84-0 |
| Molecular Formula | C10H11NO2 |
| Molecular Weight | 177.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Hydroxy-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one.
CATO supplies 8-Hydroxy-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (CAS 22246-84-0), a certified reference material (molecular formula C10H11NO2, MW 177.20 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H11NO2, 8-Hydroxy-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 177.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO2 |
| Molecular Weight | 177.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 8-Ethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 865106-49-6)
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- 7-Methoxy-3,4-dihydroquinolin-2(1H)-one (CAS 22246-17-9)
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