(2-Chloro-4-(2-methylpiperidin-1-yl)phenyl)boronic acid CAS 2225152-37-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2225152-37-2
Molecular FormulaC12H17BClNO2
Molecular Weight253.53 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Chloro-4-(2-methylpiperidin-1-yl)phenyl)boronic acid CAS 2225152-37-2 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

(2-Chloro-4-(2-methylpiperidin-1-yl)phenyl)boronic acid (CAS 2225152-37-2), molecular formula C12H17BClNO2 and molecular weight 253.53 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2-Chloro-4-(2-methylpiperidin-1-yl)phenyl)boronic acid (C12H17BClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC12H17BClNO2
Molecular Weight253.53 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentCl-containing
Nitrogen Atoms1

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