(5-Chloro-6-(3-methylpiperidin-1-yl)pyridin-3-yl)boronic acid CAS 2225152-52-1
| CAS No. | 2225152-52-1 |
| Molecular Formula | C11H16BClN2O2 |
| Molecular Weight | 254.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (5-Chloro-6-(3-methylpiperidin-1-yl)pyridin-3-yl)boronic acid (CAS 2225152-52-1), a certified reference material (molecular formula C11H16BClN2O2, MW 254.52 g/mol) for analytical method development and quality control.
The molecular framework of (5-Chloro-6-(3-methylpiperidin-1-yl)pyridin-3-yl)boronic acid (C11H16BClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5-Chloro-6-(3-methylpiperidin-1-yl)pyridin-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16BClN2O2 |
| Molecular Weight | 254.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine (CAS 1150561-74-2)
- 5-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1222522-38-4)
- 4-Chloro-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1260148-41-1)
- 3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1269440-75-6)
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Recommended Standards
- (5-Chloro-6-(2-methylpiperidin-1-yl)pyridin-3-yl)boronic acid (CAS 2225152-78-1)
- (5-Chloro-6-(4-methylpiperidin-1-yl)pyridin-3-yl)boronic acid (CAS 2225177-79-5)
- 6-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine (CAS 1973516-90-3)
- 2-(5-Chloro-2-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 635305-39-4)
- 2-(3-Chlorophenyl)-2-(piperazin-1-yl)acetic acid (CAS 1218236-71-5)
- 3-Bromo-5-cyclopropoxy-N-methylbenzamide (CAS 1243391-77-6)
- 2-((Cyclohexylmethoxy)methyl)-4-fluorobenzaldehyde (CAS 1443339-05-6)
- Azepane-3,4-diol (CAS 1822581-80-5)
- 3-(3-Aminophenyl)-3-oxetanol (CAS 1111734-98-5)
- 4-[(2-Chloro-5-fluorophenyl)methyl]morpholine hydrochloride (CAS 1881288-87-4)
- 4-Allyl-3-((2,4-dichlorobenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazole (CAS 577960-27-1)
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- 1-(1,1-Difluoroethyl)-3-ethoxybenzene (CAS 1138445-11-0)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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