(4-Chloro-2-(3-hydroxypyrrolidin-1-yl)pyrimidin-5-yl)boronic acid CAS 2225153-18-2
| CAS No. | 2225153-18-2 |
| Molecular Formula | C8H11BClN3O3 |
| Molecular Weight | 243.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-Chloro-2-(3-hydroxypyrrolidin-1-yl)pyrimidin-5-yl)boronic acid (CAS 2225153-18-2), molecular formula C8H11BClN3O3 and molecular weight 243.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (4-Chloro-2-(3-hydroxypyrrolidin-1-yl)pyrimidin-5-yl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-Chloro-2-(3-hydroxypyrrolidin-1-yl)pyrimidin-5-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11BClN3O3 |
| Molecular Weight | 243.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-3-(2-dimethylaminoethoxy)phenylboronic acid (CAS 1256355-02-8)
- (3-Chloro-4-(2-(dimethylamino)ethoxy)phenyl)boronic acid (CAS 1704080-46-5)
- 6-Chloro-5-nitro-2-(trifluoromethyl)pyrimidin-4(1H)-one (CAS 917895-54-6)
- 1-Chloro-3-fluoro-2-nitro-5-(trifluoromethyl)benzene (CAS 1226805-38-4)
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- 2-Chloro-4-fluoro-1-nitro-3-(trifluoromethyl)benzene (CAS 870065-92-2)
- 2-Chloro-N-[5-(2,2,2-trifluoroethyl)-1,3,4-oxadiazol-2-yl]acetamide (CAS 1240526-19-5)
Recommended Standards
- 3-[2[[(1,1-Dimethylethyl)dimethyl silyl]oxy]ethyl]-piperidine (CAS 146667-82-5)
- 4-Piperidineethanoltbs (CAS 204580-44-9)
- 1-triisopropylsilylpyrrol-3-ol (CAS 1394952-31-8)
- N-(Methoxymethyl)-N-(trimethylsilylmethyl)-benzylamine n-(methoxymethyl)-n-((trimethylsilyl) methyl)(phenyl)methanamine n-benzyl-n-(methoxymethyl)-n-trimethylsilylmethylamine n-methoxymethyl-n-(trimethylsilylmethyl)benzylamine n-(methoxymethyl)-n-(trimethylsilylmethyl)benzylamine benzyl-methoxymethyl-trimethylsilanylmethyl-amine n-benzyl-1-methoxy-n-((trimethylsilyl)methyl)methanamine n-benzyl-n-(methoxymethyl)-n-trimethylsilylmethyl-amine n-(methoxymethyl)-n-(trimethylsilyl)methyl(phenyl) N-Benzyl-N-(methoxymethyl)-N-trimethylsilyl-methylamine 93102-05-7 S00978 (CAS 93102-05-7)
- 2-Isocyanato-1,1-dimethoxypropane (CAS 886593-28-8)
- 1,2-Dichloro-1,1,3,3,3-pentafluoropropane (CAS 431-86-7)
- N-(4-((2-(benzo[d][1,3]dioxole-5-carbonyl)hydrazinyl)sulfonyl)phenyl)acetamide (CAS 866138-28-5)
- 1,6-Dinitroanthracene-9,10-dione (CAS 1604-42-8)
- 1-(3-(3-(P-tolyl)-1,2,4-oxadiazol-5-yl)pyridin-2-yl)piperidine-4-carboxylic acid (CAS 1223883-26-8)
- 1-(3-Methyl-1,2,4-oxadiazol-5-yl)cyclopropan-1-amine hydrochloride (CAS 1159737-11-7)
- 2-Methyl-4,4,4-trifluorobutyricacid (CAS 99783-23-0)
- Ethyl 5-((1-(pyrimidin-2-yl)piperidine-4-carboxamido)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 306978-06-3)
- N-Benzyl-4-nitro-1H-pyrazole-3-carboxamide (CAS 405278-65-1)
- Insulin Glargine (CAS 160337-95-1)
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