(5-Chloro-6-(p-tolyl)pyridin-3-yl)boronic acid CAS 2225155-38-2
| CAS No. | 2225155-38-2 |
| Molecular Formula | C12H11BClNO2 |
| Molecular Weight | 247.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, (5-Chloro-6-(p-tolyl)pyridin-3-yl)boronic acid (C12H11BClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 247.49 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (5-Chloro-6-(p-tolyl)pyridin-3-yl)boronic acid (CAS 2225155-38-2), a certified reference material (molecular formula C12H11BClNO2, MW 247.49 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (5-Chloro-6-(p-tolyl)pyridin-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11BClNO2 |
| Molecular Weight | 247.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (5-Chloro-6-(m-tolyl)pyridin-3-yl)boronic acid (CAS 2225181-53-1)
- (5-Chloro-6-(o-tolyl)pyridin-3-yl)boronic acid (CAS 2225155-14-4)
- 3-Chloro-2-(difluoromethoxy)-6-(trifluoromethyl)pyridine (CAS 1214332-87-2)
- 3-Chloro-2-difluoromethoxy-5-(trifluoromethyl)pyridine (CAS 1214349-15-1)
- 5-Chloro-2-(difluoromethoxy)-3-(trifluoromethyl)pyridine (CAS 1214379-40-4)
- 2-Chloro-3-difluoromethoxy-6-(trifluoromethyl)pyridine (CAS 1228897-80-0)
- 2-Chloro-4-(difluoromethyl)-5-(trifluoromethyl)pyridin-3-ol (CAS 1804458-61-4)
- 6-Chloro-3-(difluoromethyl)-5-(trifluoromethyl)pyridin-2-ol (CAS 1804459-19-5)
Recommended Standards
- 2,4-Dichloropyrimidine-5-sulfonyl Chloride (CAS 23920-08-3)
- 2-Bromo-5-chloro-3-(difluoromethyl)thiophene (CAS 2090725-83-8)
- 2,6-Dichloropyrimidine-4-sulfonyl chloride (CAS 1431555-21-3)
- 3-Bromo-2-chloro-5-(difluoromethyl)thiophene (CAS 2091608-75-0)
- 2-cycloheptylacetamide (CAS 14224-71-6)
- 4-(Propan-2-yl)-1,2,5-oxadiazol-3-amine (CAS 1040020-08-3)
- 2-Methyl-2-(3-methylpiperidin-1-yl)propan-1-amine (CAS 933713-01-0)
- Ertugliflozin impurity 33 (CAS 2242891-20-7)
- N,N-Dimethyl-2-(pyrrolidin-1-yl)-6-tosyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine (CAS 1081391-73-2)
- 5-Chloro-2-ethynyl-4-methoxypyrimidine (CAS 1330044-02-4)
- 2-Bromo-6-(prop-1-en-2-yl)pyridine (CAS 118775-68-1)
- methyl 3-amino-6-chlorothieno[2,3-b]1,8-naphthyridine-2-carboxylate (CAS 1353877-96-9)
- (4-Methyl-1H-imidazol-5-yl)methanethiol (CAS 70334-05-3)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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