(5-tert-Butyl-2-fluorophenyl)boronic acid CAS 2225155-59-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2225155-59-7
Molecular FormulaC10H14BFO2
Molecular Weight196.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-tert-Butyl-2-fluorophenyl)boronic acid CAS 2225155-59-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 196.03 g/mol gives (5-tert-Butyl-2-fluorophenyl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(5-tert-Butyl-2-fluorophenyl)boronic acid (CAS 2225155-59-7), molecular formula C10H14BFO2 and molecular weight 196.03 g/mol, is a CATO reference standard with documented purity and traceability.

(5-tert-Butyl-2-fluorophenyl)boronic acid (C10H14BFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-tert-Butyl-2-fluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H14BFO2
Molecular Weight196.03 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing

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