(4-Fluoro-6-(pyrazin-2-yl)pyridin-3-yl)boronic acid CAS 2225169-43-5
| CAS No. | 2225169-43-5 |
| Molecular Formula | C9H7BFN3O2 |
| Molecular Weight | 218.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-Fluoro-6-(pyrazin-2-yl)pyridin-3-yl)boronic acid (C9H7BFN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(4-Fluoro-6-(pyrazin-2-yl)pyridin-3-yl)boronic acid (CAS 2225169-43-5), molecular formula C9H7BFN3O2 and molecular weight 218.98 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4-Fluoro-6-(pyrazin-2-yl)pyridin-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7BFN3O2 |
| Molecular Weight | 218.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- (2-Fluoro-6-(pyrimidin-5-yl)pyridin-3-yl)boronic acid (CAS 2225172-43-8)
- 4-Fluoro-3-sulfamoylphenylboronic acid (CAS 1036738-32-5)
- (4-Fluoro-3-(bromomethyl)phenyl)methanol (CAS 1378867-70-9)
- 2-Fluoro-3-methoxybenzyl bromide (CAS 447463-56-1)
- 3-Fluoro-5-methoxybenzyl Bromide (CAS 914637-29-9)
- 5-Fluoro-2-methoxybenzyl Bromide (CAS 700381-18-6)
- 2-(4-Fluoro-3-(trifluoromethoxy)phenyl)acetonitrile (CAS 1020718-23-3)
- 2-(5-Fluoro-2-(trifluoromethoxy)phenyl)acetonitrile (CAS 1092460-90-6)
Recommended Standards
- 3-Iodo-1H-pyrazole-4-carbonitrile (CAS 827316-44-9)
- 5-Iodo-1H-pyrazole-3-carbonitrile (CAS 1533442-33-9)
- 5-Iodofuran-2-carbonitrile (CAS 57240-58-1)
- 2,3-Dichlorofuro[3,4-b]pyrazine-5,7-dione (CAS 144692-85-3)
- 2-(2,3-difluorophenyl)-N-(2-iodoethyl)acetamide (CAS 1566706-03-3)
- Tetrahydrothiophene (CAS 110-01-0)
- 5-Iodopyrimidine-2,4,6-triol (CAS 54124-12-8)
- (R)-(-)-2-(Methoxymethyl)oxirane (R)-(-)-Glycidyl methyl ether (R)-(-)-Methyl glycidyl ether 64491-70-9 (CAS 64491-70-9)
- N-Cyclohexyl 1-BOC-piperidine-4-carboxamide (CAS 757949-48-7)
- (3-Methoxyphenyl)methanesulfonyl chloride (CAS 163295-76-9)
- 3-Chloro-5-(trifluoromethoxy)benzaldehyde (CAS 433926-48-8)
- 2,4-Dicyclopropyl-6-(piperazin-1-yl)pyrimidine (CAS 1713462-67-9)
- N-(3-(2,4,6-trichlorophenoxy)prop-1-yn-1-yl)piperidine-1-carbothioamide (CAS 23341-91-5)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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