(4-Chloro-2-(2-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid CAS 2225170-02-3
| CAS No. | 2225170-02-3 |
| Molecular Formula | C11H7BClF3N2O2 |
| Molecular Weight | 302.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-Chloro-2-(2-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid.
(4-Chloro-2-(2-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid (CAS 2225170-02-3), molecular formula C11H7BClF3N2O2 and molecular weight 302.44 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (4-Chloro-2-(2-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid (C11H7BClF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 302.44 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-Chloro-2-(2-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7BClF3N2O2 |
| Molecular Weight | 302.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (4-Chloro-2-(3-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid (CAS 2225180-15-2)
- (4-Chloro-2-(4-(trifluoromethyl)phenyl)pyrimidin-5-yl)boronic acid (CAS 2225175-97-1)
- 2-Chloro-3-fluoro-5-iodo-6-methoxy-4-pyridinamine (CAS 2864418-62-0)
- 6-chloro-3-iodo-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one (CAS 2131742-03-3)
- 2-Chloro-3,5-dibromo-6-fluorotoluene (CAS 1160574-53-7)
- 2-Chloro-3,5-dibromo-4-fluorotoluene (CAS 1160574-79-7)
- 5-Chloro-2,4-dibromo-3-fluorotoluene (CAS 1356113-79-5)
- 2-chloro-3-[2,6-dichloro-4-(trifluoromethyl)phenyl]propanenitrile (CAS 258518-45-5)
Recommended Standards
- (3aR,6R,6aR)-6-(((tert-Butyldimethylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one (CAS 75467-36-6)
- 5-((3,5-Dimethylphenyl)thio)-2-(hydrazonomethyl)-4-isopropyl-1-methyl-1H-imidazole (CAS 178979-00-5)
- 7-(benzenesulfonyl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 1630906-56-7)
- 1-(3-Cyanophenyl)-3-((1R,2R)-2-(dimethylamino)cyclohexyl)thiourea (CAS 834917-27-0)
- S-(1H-Benzo[d]imidazol-2-yl)-N-ethylthiohydroxylamine (CAS 149679-62-9)
- N5,N7-Diethyl-3-((4-methylbenzyl)thio)-[1,2,4]triazolo[4,3-a][1,3,5]triazine-5,7-diamine (CAS 898414-59-0)
- (R)-1-(2,5-difluorophenyl)pentan-1-amine (CAS 1212883-70-9)
- n-Propyl-2,3-dihydro-1h-inden-2-amine hydrochloride (CAS 74220-93-2)
- Milnacipran Impurity 13 (CAS 19532-98-0)
- 3,4-Dimethyl-1H-pyrazol-5-amine (CAS 1423187-58-9)
- 1-(2-methoxyethyl)-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 1343805-24-2)
- 2-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole (CAS 1029684-35-2)
- Nicotelline (CAS 494-04-2)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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