(2-Chloro-6-(piperidin-4-yl)pyridin-4-yl)boronic acid CAS 2225170-16-9
| CAS No. | 2225170-16-9 |
| Molecular Formula | C10H14BClN2O2 |
| Molecular Weight | 240.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2-Chloro-6-(piperidin-4-yl)pyridin-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2-Chloro-6-(piperidin-4-yl)pyridin-4-yl)boronic acid (CAS 2225170-16-9), molecular formula C10H14BClN2O2 and molecular weight 240.49 g/mol, is a CATO reference standard with documented purity and traceability.
(2-Chloro-6-(piperidin-4-yl)pyridin-4-yl)boronic acid (C10H14BClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14BClN2O2 |
| Molecular Weight | 240.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine (CAS 1009378-52-2)
- 3-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine (CAS 1162261-98-4)
- (3-Chloro-4-(cyclopentyloxy)phenyl)boronic acid (CAS 1228181-29-0)
- (4-Chloro-2-(cyclopentyloxy)phenyl)boronic acid (CAS 1256355-05-1)
- 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine (CAS 1259298-22-0)
- 4-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1264138-50-2)
- 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1310404-27-3)
- 3-Chloro-4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenol (CAS 1479007-22-1)
Recommended Standards
- (2-Chloro-6-(piperidin-3-yl)pyridin-4-yl)boronic acid (CAS 2225152-01-0)
- (4-Chloro-2-cyclohexylpyrimidin-5-yl)boronic acid (CAS 2225175-88-0)
- (2-Chloro-4-(piperazin-1-yl)phenyl)boronic acid (CAS 2225155-99-5)
- (5-Chloro-6-(piperidin-1-yl)pyridin-3-yl)boronic acid (CAS 2225178-79-8)
- 2-Hydroxy-N-(4-methoxyphenyl)-2-phenylacetamide (CAS 10295-49-5)
- 2-Bromo-5-methylthiazole-4-carbaldehyde (CAS 1379318-90-7)
- 1-(4-Chlorophenyl)-3-(4-fluorophenyl)urea (CAS 404-51-3)
- 1-(1H-Indol-2-yl)-1-(pyridin-4-yl)ethan-1-ol (CAS 79820-57-8)
- 4-Methoxy-1H-indole-5-carbaldehyde (CAS 1367982-08-8)
- (2,5,6-Triaminopyrimidin-4-yl)methanol (CAS 33704-86-8)
- Ethyl Olivetolate (CAS 38862-65-6)
- Methyl (2S,4S)-4-(N-(4,4-dimethylcyclohexyl)pivalamido)pyrrolidine-2-carboxylate (CAS 1002731-95-4)
- Tedizolid Impurity 87 (CAS 2095840-86-9)
- Tirzepatide (CAS 2023788-19-2)
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