(2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid CAS 2225170-30-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2225170-30-7
Molecular FormulaC6H4BBrF3NO2
Molecular Weight269.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid CAS 2225170-30-7 chemical structure

Description

The occurrence of (2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225170-30-7), molecular formula C6H4BBrF3NO2 and molecular weight 269.81 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid (C6H4BBrF3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2-Bromo-6-(trifluoromethyl)pyridin-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4BBrF3NO2
Molecular Weight269.81 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF/Br-containing
Nitrogen Atoms1

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