(6-Bromo-4-fluoropyridin-3-yl)boronic acid CAS 2225171-58-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2225171-58-2
Molecular FormulaC5H4BBrFNO2
Molecular Weight219.80 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(6-Bromo-4-fluoropyridin-3-yl)boronic acid CAS 2225171-58-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 219.80 g/mol gives (6-Bromo-4-fluoropyridin-3-yl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(6-Bromo-4-fluoropyridin-3-yl)boronic acid (CAS 2225171-58-2) is a high-purity analytical reference standard with the molecular formula C5H4BBrFNO2 and a molecular weight of 219.80 g/mol.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, (6-Bromo-4-fluoropyridin-3-yl)boronic acid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (6-Bromo-4-fluoropyridin-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H4BBrFNO2
Molecular Weight219.80 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF/Br-containing
Nitrogen Atoms1

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