(5-Cyclohexyl-2-fluorophenyl)boronic acid CAS 2225175-07-3
| CAS No. | 2225175-07-3 |
| Molecular Formula | C12H16BFO2 |
| Molecular Weight | 222.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(5-Cyclohexyl-2-fluorophenyl)boronic acid (CAS 2225175-07-3) is a high-purity analytical reference standard with the molecular formula C12H16BFO2 and a molecular weight of 222.06 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (5-Cyclohexyl-2-fluorophenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H16BFO2 |
| Molecular Weight | 222.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Cyclohexyl Standards
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Recommended Standards
- 2-(2-Bromothiazol-4-yl)acetic acid (CAS 62557-07-7)
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- 2-Amino-5-bromothiophene-3-carboxylic acid (CAS 1784352-12-0)
- 4,4'-(Naphthalene-1,4-diyl)bis(2-hydroxybenzoic acid) (CAS 2250341-24-1)
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- Pyridazine-3,6-dicarboxylic acid hydrate (CAS 849223-55-8)
- 2-(Benzo[d]thiazol-2-ylthio)-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)acetamide (CAS 1396783-51-9)
- 5-Bromo-6-fluoro-1-benzofuran (CAS 1427417-54-6)
- 3-(4-Bromo-2-ethoxyphenyl)acrylic acid (CAS 1094474-73-3)
- 8-Methoxy-6-methylquinolin-4-ol (CAS 496875-55-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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