(5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid CAS 2225175-82-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2225175-82-4
Molecular FormulaC9H8BFN2O2
Molecular Weight205.98 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid CAS 2225175-82-4 chemical structure

Description

(5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid (CAS 2225175-82-4), molecular formula C9H8BFN2O2 and molecular weight 205.98 g/mol, is a CATO reference standard with documented purity and traceability.

(5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid (C9H8BFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-Fluoro-2-(1H-pyrrol-1-yl)pyridin-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H8BFN2O2
Molecular Weight205.98 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms2

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