(5-Cyclopropyl-2-methyl-4-(trifluoromethyl)phenyl)boronic acid CAS 2225176-12-3
| CAS No. | 2225176-12-3 |
| Molecular Formula | C11H12BF3O2 |
| Molecular Weight | 244.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(5-Cyclopropyl-2-methyl-4-(trifluoromethyl)phenyl)boronic acid (CAS 2225176-12-3), molecular formula C11H12BF3O2 and molecular weight 244.02 g/mol, is a CATO reference standard with documented purity and traceability.
(5-Cyclopropyl-2-methyl-4-(trifluoromethyl)phenyl)boronic acid (C11H12BF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12BF3O2 |
| Molecular Weight | 244.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Cyclopropyl Standards
- (2-Cyclopropyl-4-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225179-41-7)
- (3-Cyclopropyl-2-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225172-46-1)
- (4-Cyclopropyl-2-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225170-41-0)
- (5-Cyclopropyl-2-methyl-3-(trifluoromethyl)phenyl)boronic acid (CAS 2225180-97-0)
- 1-Cyclopropyl-3-iodobenzene (CAS 1260852-26-3)
- 1-Cyclopropyl-2-iodobenzene (CAS 57807-29-1)
- 1-Cyclopropyl-4-iodobenzene (CAS 57807-27-9)
- N-Cyclopropyl 2-bromo-6-fluorobenzylamine (CAS 1355247-19-6)
Recommended Standards
- 1-(Difluoromethyl)-3-iodobicyclo[1.1.1]pentane (CAS 2363075-15-2)
- 4-Bromo-5-fluoroindoline-2,3-dione (CAS 2044902-62-5)
- 5,5-Dimethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborinane (CAS 378185-01-4)
- (3-Cyclobutyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225169-62-8)
- 2-Cyano-N-propylacetamide (CAS 52493-35-3)
- Dihydro Artemisinin Dimer (CAS 150358-71-7)
- Methyl 4-hydroxybicyclo[2.2.2]octane-1-carboxylate (CAS 23062-53-5)
- 1-Cyclopentylethane-1-sulfonyl chloride (CAS 1249542-29-7)
- 1-(2-Methyl-2,3-dihydrobenzofuran-5-yl)-N-((tetrahydrofuran-2-yl)methyl)methanamine (CAS 878046-64-1)
- 1-(3-aminopropyl)pyrrolidine-2,5-dione hydrochloride (CAS 1211465-69-8)
- 4-Chloro-N-(2,5-dimethyl-1H-pyrrol-1-yl)benzamide (CAS 672950-20-8)
- 1-((2R,4S,5R)-5-(((Tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione (CAS 129816-30-4)
- 1-((5-Cyclopropyl-1,2,4-oxadiazol-3-yl)methyl)piperidin-4-amine (CAS 1247617-23-7)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com